Teams involved in the LIA-ROPSE

The C3M is dedicated to cancer and cardio-metabolic diseases. C3M includes three research axes:

• Proliferation, cell death, differentiation and cancer;
• Metabolic diseases;
• Infection and inflammatory responses.

ECOSEAS is specialized in fundamental and applied marine ecology. This laboratory works in the Mediterranean Sea and addresses the functioning of ecosystems from both a theoretical and practical perspective; marine species biology and ecology; the modification of marine fauna and flora under the influence of global change; marine protected areas; management of artisanal fisheries and others.

GREDEG scientific activities combine economic, legal and managerial perspectives around innovation and knowledge. GREDEG favors multidisciplinary approaches, and is currently developing joint work with biologists and physicists.

The iBV studies fundamental questions in life and health sciences with multidisciplinary approaches in molecular biology, cell biology, genetics, imaging, genomics and bioinformatics.

The ICN is organized into four research teams:

• The “Aromas - Perfumes - Synthesis - Modeling” team, which develops new molecules that make up aromas and perfumes;
• The “Bioactive Molecules” team, which focuses on bioactive molecules with antiviral or antitumor properties;
• The “Human and Environmental Radiochemistry” team, which studies the impact of nuclear power on the environment and on humans;
• The “Eco-Compatible Materials and Polymers” team studies eco-compatible materials and polymers with a sustainable development approach.

The activities carried out at IRCAN aim to understand the biological mechanisms linking aging and cancer, with particular attention paid to the role played by stress, whether related to the environment or lifestyle.

The Lφ2M laboratory develops projects focused on renal, vascular, muscular, neurosensory and bone physiology as well as inflammation and cancer. This research is giving rise to clinical applications for chronic diseases, osteoporosis, ischemia, transplantation and cancer.

The LJAD laboratory is specialized in the development of fundamental mathematics, their applications and interactions with other disciplines (physics, biology, neurosciences, medicine, environment, etc.).

The activities carried out at the TIRO-MATOs Laboratory focus on the study of 2 major elements in radio-toxicology which are iodine and uranium. The projects developed concern in particular the effects on 2 target organs of these elements with the thyroid for iodine (TIRO) and the bone for uranium (MATOs). These studies allow an improvement of the knowledge of the functioning and the regulation of these organs as well as an analysis of the deregulations associated with the pathologies.

The marine biology department is made up of three research teams:

• The environmental economics team (economic consequences of climate change in the marine environment);
• The coral physiology/biochemistry team (initial activities focused on biomineralization);
• The coral ecophysiology team (understanding the effects of climatic disturbances on coral ecosystems with a particular interest in calcification and symbiosis).

The medical biology department is made up of 4 research teams:

• The Human Health division aims to energize and promote clinical research;
• The resistance mechanisms to targeted therapies team (discovery of markers indicative of sensitivity to cancer treatments);
• The tumor hypoxia and metabolism team (hypoxic and nutritional stress in rapidly growing tumors);
• The ecosystems and immunity team (understanding the host-pathogen relationship in various models).

The polar biology department is made up of two research axes:

• The main objective of the "Artificial Intelligence" axis is to develop new theoretical models and artificial intelligence tools to better understand, and therefore better anticipate the effects of environmental stresses (in particular those related to climate change) on ecosystems polar.+
• The "Observatory of the Living Organisms" axis focuses on the ecological and evolutionary processes that shape populations. In order to track penguin populations under conditions undisturbed by humans, approximately 25,000 penguins have been tagged using RFID chips and are being tracked using antennas or automated gateways.